A falta de compreensão sobre as diferenças culturais e linguísticas de pessoas que apresentam a surdez como marca corporal pode ser uma barreira para psicólogos e equipes de pesquisa em saúde que trabalham com essa população. Seguindo a metodologia PRISMA de pesquisa sistemática este artigo realiza uma revisão em periódicos nacionais e internacionais a fim de caracterizar a atual situação de atendimento psicoterápico para surdos e seu contexto. Apresentamos o resultado de uma busca feita em periódicos indexados nas bases de dados SciELO e PUBmed no período de 2006 a 2016. Os principais resultados indicam que o conceito socioantropológico de surdez prevalece sobre o modelo médico-clínico, que as temáticas de maior interesse são a linguagem e a língua, o desenvolvimento cognitivo e as relações familiares. A maioria dos estudos encontrados no período de recorte dessa revisão conforma um leque que vai da fusão entre o pensamento, o discurso e seu resultado cultural em um dos extremos, a uma separação e a segregação de ambos, no outro. Discute-se a necessidade de ampliar a produção científica na área.

The lost of quality of life in Brazil and in the world is due to the consequences of mental disorders (MD). These disorders have heterogeneous symptoms and a multifactorial etiology. We carried out a descriptive and retrospective observational study with the aim of characterizing the profiles of psychiatric patients in the northwest of São Paulo State. We analyzed data from the Psychiatry Outpatient Clinic of the Hospital de Base of São José do Rio Preto, a teaching hospital, under the administration of the XV Regional Health Department (DRS XV). We typify the appointments that occurred between the years 2018 to 2020, observing the predominant disorders in a sample of 8,384 appointments. Generalized Anxiety Disorder (GAD) represents the highest recurrence. Most patients are female and the mean age was 45 years. The prevalent symptoms are sadness, anxiety, and irritability. The most commonly used medications are SSRIs (Selective Serotonin Reuptake Inhibitors). The epidemiological characterization of MD in the northwest of São Paulo state indicates a symptomatic comorbidity. These data provide evidence for the establishment of more specific protocols in mental health and advocate a dimensional transdiagnostic approach according to aspects of the new review proposed by the ICD-11.

Background Ocular toxoplasmosis (OT) is a frequent clinical manifestation due to infection by Toxoplasma gondii. It is characterized by an inflammatory process involving macrophages activated by pro-inflammatory cytokines. The expression of microRNAs takes place during the inflammatory process and, among them, miRNA 511 regulates the activation of macrophages. This study evaluated the expression of miRNA 511_5p in patients with OT and healthy controls. Methods A total of 361 patients from the Hospital de Base of Fundação Faculdade de Medicina de São José do Rio Preto were enrolled and divided into four groups: G1–patients with active ocular lesions and reagent serology for T. gondii; G2–patients with scars and reagent serology for T. gondii; G3–patients without ocular lesions or scars and reagent serology for T. gondii; G4–patients without ocular lesions or scars and non-reagent serology for T. gondii. All patients underwent clinical and laboratory evaluation to confirm the diagnosis of OT. Serology tests, RNA extraction and cDNA synthesis were performed. Results The miRNA 511_5p levels were compared among the groups. The G1 group showed a high blood plasma concentration of miRNA 511_5p (mean 22.34) compared with the G2 (4.65), G3 (8.91) and G4 (3.52) groups (p<0.0001). Conclusion These data suggest that miRNA 511_5p has significant potential as a biomarker for OT.