The contour error cross-coupling control is very important to improve contour accuracy for the five-axis computer numerical control machine. The change in cutter orientation can cause the nonlinear motion of cutter tip, so the contour error calculation and compensation are very complex. For the five-axis computer numerical control machine with dual rotary tables, the forward kinematics model and inverse kinematics model are set up, and the influence laws of feed axis deviation to cutter tip deviation and cutter orientation deviation are studied. Then the simple and accurate calculation models for cutter tip contour error and cutter orientation contour error are established. Finally, the novel contour error cross-coupling control method based on kinematics model is developed. The experimental results show that the developed method can effectively improve contour accuracy of the five-axis computer numerical control machine.