Objective:To compare the effects of oxytocin and dinoprostone used in labor induction on fetal blood gas parameters. Material and Methods: This prospective randomized trial involved108 women who completed 37 gestational weeks and who required labor induction prior to normal vaginal birth. Labor was induced in 57 women with an intravenous low dose oxytocin regimen and in 51 with intravaginal dinoprostone (PGE 2 ). Following childbirth, umbilical artery blood gas was analyzed, with pH, pCO 2 , pO 2 , HCO 3 and base excess (BE) compared in the two groups.Results: Mean age and obstetrical data (gravidity, parity, gestational weeks and birthweight) were similar in the two groups (p>0.05). All infants had 1 and 5 minute APGAR scores ≥7. Umbilical artery blood pH was similar in the oxytocin and dinoprostone groups (7.31±0.07 vs. 7.31±0.05, p=0.780), as were the other blood gas parameters (pCO 2 , pO 2 , base excess and HCO 3 ; p>0.05 each). Conclusion:Induction of labor with either oxytocin or dinoprostone in women with uncomplicated term pregnancies had no adverse effects on umbilical artery blood gas parameters. (J Turkish-German Gynecol Assoc 2012; 13: 257-60) Key words: Oxytocin, dinoproston, umbilical artery blood gas, labor induction, pH Received: 13 August, 2012 Accepted: 18 November, 2012 Amaç: Bu çalışmada amacımız, doğum indüksiyonunda kullanılan iki metod olan oksitosin ve dinoprostonun fetal kan gazı parametreleri üzerine olan etkilerinin karşılaştırılmasıdır. Gereç ve