PRP application could be considered as an effective procedure for facial skin rejuvenation.

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Background The application of heat, used to straighten the typically coiled hair, has long been hypothesized to play a role in the etiologic factor for central centrifugal cicatricial alopecia (CCCA). The aim of this study was to evaluate the effect of thermal hair straightening on hair loss pattern in Asian women exist. Materials and methods Thirty‐five patients with hair loss who have been using hair straightening devices and 25 patients with telogen effluvium were enrolled in this prospective study. Laboratory analysis and dermatoscopic findings were used to compare these groups. Results The peripilar white halo around hairs, peripilar dark/gray halo around follicular orifices, the predominance of a single hair perifollicular unit (FU), hair diameter diversity, the thin miniaturized hair, interfollicular pinpoint white dots, and white patches were statistically higher in hair straightener group (P < 0.001). White patches of the scalp increased by the time of the application of these devices (P < 0.01). White patches of vertex region were significantly higher than the midfrontal region (P < 0.01). Conclusion The common side effects of thermal hot comb strengtheners’ were summarized as damage to the hair shaft; decreasing in the brightness of the hair, burns, and scars on the scalp; and lastly CCCA‐like hair loss.

Background: Systemic therapies commonly used in adult psoriasis are mostly used only off-label in children and little is known about the efficacy and tolerability of these drugs in this population. In this study, we aimed to evaluate the efficacy and safety of systemic treatments in pediatric patients with psoriasis. Methods: Data were obtained retrospectively from the Department of Dermatology, Ondokuz Mayis University, School of Medicine between 2010–2019. Our study consisted of 742 pediatric patients (age ≤18 years) with psoriasis. Demographic data, adverse events of systemic treatments and healing periods were considered. Results: A total of 195 patients received systemic treatment. The mean age of onset of disease and the initiation of systemic therapy were 9.68±4.62 and 11.33±4.38 years, respectively. Patients received methotrexate (n=52, 26.67%), cyclosporine (n=18, 9.24%), acitretin (n=106, 54.35%) and others (biologics and/or one of conventional treatments) (n=19, 9.74%) as systemic therapy. Adverse events occurred in 12 patients (incidence of 6.15%, and its related 95% confidence interval of 2.75%, 9.56%) and nine of them had to discontinue the medication due to those adverse events. Healing periods calculated in the remaining 186 patients were 13.25±5.87, 10.85±5.67, 11.05±7.00, and 9.41±4.16 (mean±SD) weeks for acitretin, methotrexate, cyclosporine, and others, respectively. No statistically significant differences were noted between the treatments regarding the healing periods. Conclusion: All treatments were effective and none of them was superior in terms of the healing period. Systemic treatments used in adults can also be used in pediatric patients with psoriasis with similar efficacy and safety rates as long as routine monitoring is provided.

The main aim of this study was to observe the sensitivity for discriminating old and new words for three word types (critical, related, unrelated) in Deese-Roediger-McDermott (DRM) lists. With this aim, for all three kinds of DRM paradigm word types we paired one presented word on study phase against one word that was not presented in each trial in a two-alternative forced choice test. We tried to answer three questions related to false positive responses in the DRM paradigm: First, do false positives stem from a response bias or do the participants have lower sensitivity to distinguish nonstudied from studied words? We used a forced-choice recognition task in order to isolate the effect of sensitivity. Second, is a potential reduction in sensitivity related to recollection or familiarity? We asked participants to classify their responses as "remember", "know", or "guess" in order to explore this issue. Third, is there a difference in sensitivity for prior study in auditory and visual list learning tasks and their distribution into the three kinds of recognition responses? For the first question of the study as a result of the research we observed lower sensitivity for the critical words of the DRM lists than words in unrelated lists. When the findings they classified in terms of recognition memory were examined, it was observed that remember responses clearly differentiated for the three types of words. It was an answer for the second question of the study that sensitivity reduction was related with recollection more than familiarity. Modality did not make a difference in any measure.