Inner ear involvement may occur in systemic autoimmune diseases. Although there are studies evaluating hearing in psoriasis patients, its effect on the balance system is not clear. The aim of the present study was to evaluate the audiovestibular system in psoriasis patients without joint involvement. In this prospective study, the audiovestibular system of 32 psoriasis patients without joint involvement and 35 healthy volunteers were evaluated. The severity of the disease was determined by the psoriasis area severity index (PASI). There was no significant difference between the groups in terms of hearing test results, while the abnormal caloric test response was significantly higher in the psoriatic patients. PASI scores of psoriasis patients with abnormal caloric test results were higher than those with normal caloric test response. In psoriasis patients without joint involvement, the hearing was not affected, but the vestibular system was. The severity of the disease was associated with vestibular involvement. Particularly in patients with severe psoriasis, it must be considered that the vestibular system might be affected, and vestibular evaluations should be performed.
Alopecia areata (AA) is an autoimmune disease that results in hair loss because of immune-mediated damage to the hair follicles.Other autoimmune diseases such as autoimmune thyroiditis, psoriasis, vitiligo, systemic lupus erythematosus and pernicious anaemia may accompany AA. It has been reported that the inner ear may be affected in these systemic autoimmune diseases, including AA. [1][2][3][4][5][6] It has been reported that follicular melanocytes are an important target for autoimmunity in AA patients. 7,8 Bulb melanocytes are essential for the follicular cycle and loss of melanocytes can result in hair loss. However, it is not clear whether melanocytes are primarily affected in the pathogenesis of AA or affected secondarily because of autoimmune damage in the hair follicle. Apart from the hair bulb, melanocytes are also found in the epidermis, the uveal tract and retinal pigment epithelium in the eye, the inner ear and the leptomeninges. 2 Just as melanocytes in the hair bulb play an important role in the follicular cycle, melanocytes in the inner ear are also
Medicinal leech application is a common traditional therapy used for various disorders in many cultures for thousands of years. Although it is usually a safe method, serious side effects can also be seen. As a rare side effect of this method, cutaneous pseudolymphoma is a reactive skin disease caused by foreign antigens, infectious processes and arthropod bites. Idiopathic cases sometimes can be seen. In this article, we present a case of cutaneous pseudolymphoma in an elderly woman with multiple nodules over her lumbar region emerging after leech application.Tıbbi sülük uygulaması binlerce yıldır birçok kültürde çeşitli hastalıkların tedavisinde kullanılan yaygın bir geleneksel tedavi yöntemidir. Genellikle güvenli bir yöntem olmasına rağmen, bazen ciddi yan etkiler de görülebilir. Bu metodun nadir bir yan etkisi olarak kutanöz psödolenfoma, yabancı antijenler, enfeksiyöz süreçler, artropod ısırıkları ve bazen idiopatik nedenlerle oluşan reaktif bir deri hastalığıdır. Bu yazıda, sülük uygulaması sonrası çok sayıda nodülü olan ve kutanöz psödolenfoma tanısı konulan bir kadın olguyu sunuyor ve literatürü gözden geçiriyoruz.Anahtar kelimeler: Psödolenfoma, tıbbi sülük, geleneksel yöntemler.
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