E. Colonic duplication in an adult who presented with chronic constipation attributed to hypothyroidism. World

Small and medium enterprises are the main institutional medium of the European economy. This is also recognized by the government of the Republic of Croatia, which emphasizes their importance and values their dynamism and capability for revitalizing the Croatian economy, and supports this by ways of subsidies. But, for all the effort, the economic position of small and medium enterprises in the terms of globalization is becoming more complex and uncertain, limited by time and more demanding. This does not correspond with the thesis which states that in the environment and conditions of the modern market economy, which is dynamised by progress in science, technology, information and communication, entrepreneurship has manifested a progressive dimension with the character and needs of all economic activity, as well as a tendency to achieve set objectives and generate change. Recently, after the repeated recession, which was encumbered by the effects of the one before, the conditions of doing business and survival for small and medium enterprises have changed significantly in a negative sense. So, there is a justified cause for questioning earlier stances about small and medium enterprises and their capability to be a motor of development of the Croatian economy, as well as to reevaluate their influence in the context of GDP growth, to focus on the importance and prevalence of certain sectors of the economy, to critically evaluate economic measures which do not lead to a reduction in unemployment and to define the requirements for future development of the small and medium enterprises, which implicates the increased economic efficiency, quality and living standards.

Lately, an interest for space tourism in the world has been growing rapidly. It is a reflection of interest for tourist spending which strives for consumption of until now unrealized tourist experiences and destinations on one side, as well as implementation of a proactive politics of inventive entrepreneurship which has a desire to invest, and also makes an enormous profit off of space tourism on the other. Our current results of different studies around the world confirm a wide interest of tourist spending for this sort of selective tourism, so from that point of view, the first and main prerequisite is fulfilled. But, for space tourism to be accepted as a "mass movement", it is necessary to broadly adjust the prices of earlier, mainly individual arrangements, which mostly premiums lowering costs of manufacturing space shuttles, as well as their launch costs. In addition, it is necessary to systematically solve a whole bunch of open questions regarding legal, administrative, health, as well as, for example, insurance issues. In the spectrum of this field of research authors were trying to analytically, but still critically aspect the relevance of this, primarily futuristic industrial tourism "project", and also interpret some of their visions of the given issue.Despite all the open speculations, it is undeniable that space tourism will have a future, that in the long term it will develop with the programmed fazes of development and that the expansion of space tourism will causally manifest onto all the segments of economic and social life.