No abstract

BACKGROUND: This study longitudinally evaluated the IgG response against the N-protein after the onset of COVID19 infection. We determined the kinetics and magnitude of the antibody response against SARS-CoV-2 in conrmed COVID-19 patients who were the rst infected with SARS-CoV-2 in Krapina-Zagorje county in northern Croatia. MATERIALS AND METHODS: We studied 177 blood specimens from 51 patients who tested positive by PCR for COVID-19 and provided longitudinal blood samples over a duration of several months, allowing to evaluate the IgG response against the N-protein. SARS-CoV-2 IgG assay was interpreted as positive (ratio1.4 S/C) or negative (ratio<1.4 S/C). RESULTS: The majority of subjects (48/51) reported symptomatic disease. Among the 49 patients who underwent serological antibody testing at rst time point (median: 47 days), 47/49 were positive for IgG 6.02 (0.24-10.54 S/C), while at sixth time point (median: 275 days) 4/16 patients were positive for IgG, 9/16 were in grey zone, and 3/16 were negative. Using Wilcoxon statistical analysis we found statistically signicant decrease of SARS-CoV-2 N-protein IgG indices between the rst and the sixth time point (median signal to cut-off ratio, S/C, 8.18 IQR 6.91, 9.51 to 0.94 IQR 0.56, 1.18, P=0.001). CONCLUSIONS: We claried the kinetics and magnitude of the antibody response against SARS-CoV-2 in conrmed COVID-19 patients. Our results provide critical evidence that N-protein IgG response persists in the majority of patients for at least six to eight months after COVID19 infection.

Border Gateway Protocol (BGP) is the actual routing inter-domain protocol in the Internet. The size, heterogenity and changebility that characterize todays Internet put always increasing requirements on BGP performance. The research community has already reported the unwanted characteristics of BGP like low integrity and slow convergence through theoretichal analyzes andd empirical measurements. Simulations allow for more realistic and flexible experiments than the theoretichal approach and also lower costs than the measurements in real life environments. The first part of this work describe theoretically characteristics and problems related to BGP nd also expectations of the today Internet users to real time applications (like VoIP). The second part concentrates in identifying and implementing of the elements for creating an integrated simulation environment for evaluating dhe effects of slowconvergence of BGP in these applications. At last it is evaluated the created environement through some small scale simmulations that try to model the now days Internet Structure.

The paper deals with specific qualities of communication forms on selected websites (24 sata. hr, Index. hr, The Guardian and The New York Times) in accordance with the theoretical instruments of social semiotics. We find that fundamental principles of this discipline are of paramount importance in trying to explain the significance and influence of media messages on shaping awareness of the world. We have followed poststructuralist semiotic tendencies, and we have tried to emphasize the need for signs to be observed primarily as dynamic formations, as semiotic resources which are used in the process of creating meaning and which represent the cornerstone of multimodal content as the third level of virtual communication on which we basically founded this paper. Furthermore, given the context, the way, the character and the occurrence frequency of the term terrorism on the aforementioned websites in a two-month period, we tried to show how certain topics cross narrower, in this case political issues and become a global interest that simultaneously communicates in several segments and creates a specific sign system that spreads to very different areas of interest by corresponding and managing different areas of knowledge while simultaneously influencing the design of our political, ideological, social and cultural attitudes.

Mediji su 2020. godinu počeli različitim nagađanjima o proročanstvima o virusu COVID-19, najavljenima kroz film i roman pa čak i Bibliju. Nisu se libili poistovjetiti posljedice kuge s onima od virusa COVID-19 čime su potaknuli različite rasističke i ksenofobne ispade u komentarima čitatelja. U ovom radu je kroz aspekt intertekstualnosti i intermedijalnosti opisana situacija u svjetskom medijskom prostoru tijekom pandemije COVID-19. Intenzivno korištenje intertekstualnosti i intermedijalnosti uzrokovano je zadovoljavanjem potreba publike da kroz povezivanje poznatih i novih sadržaja smanji strah od nepoznatoga i familijarizira se s novim pojmovima i novim situacijama. Prevelika količina nepoznanica koja je postojala osobito početkom pandemije morala se nadomjestiti ranijim iskustvima kako bi publika lakše usvojila željene obrasce ponašanja. Nakon što su obrasci ponašanja usvojeni, počinju se koristiti i u komercijalne svrhe.