I -0.5 I I I 0 5 10 I S SECONOARY PERIOD, DAYS FIG. 2. Body wt gains of mature but sexually inaetive male turkeys following adiiiiiiistration of tmtostrroiie propionate (TP), and of pregnant mares' sewn1 with the androgen (PMS + TP) ;:ilso, Iwdy v t cliaiigt.5 of uninjected and P318 injected coiitro,l birds. ment until the outmme of these tests is known, attractive though some possible implications of a gonadotrophically conditioned augmentation effect may appear to be.
Summary.Following preliminary treat men t with pregnant mares' serum, body weight responses of immature and mature, but sexually inactive, male turkeys to testosterone propionate were considerably augmented when the androgen was administered concurrently with pregnant mares' serum. The serum alone was without appreciable effect on body weight. Whether the observed augmentation is an effect of gonadotrophin or of some other constituent of the serum is not known.
The XYZ phenomenon may be defined as Brown-Pearce rabbit tumor responsible for the increased incidence and more rapid incre-the phenomenon is selective, filtrable (Berkement of local and metastatic transplanted feld "V") and thbermolabile (56°C) ;5-7 that tumors following the prior injection in the in Bashford mouse mammary carcinoma same or distant sites of an extract from th$e 638*9 is likewise highly selective or specific.1°-12 homologous Talley of the laboratory staff of the Baptist Hospital in the care of the animals, recording of data and preparation of histologic material is acknowledged with thanks.
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