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Global pollution is calling for advanced methods to remove contaminants from water and wastewater, such as TiO 2 -assisted photocatalysis.  The environmental applications of titanium dioxide have started after the initial TiO 2 application for water splitting by Fujishima and Honda in 1972. TiO 2 is now used for self-cleaning surfaces, air and water purification systems, microbial inactivation and selective organic conversion. The synthesis of titanium dioxide nanomaterials with high photocatalytic activity is actually a major challenge. Here we review titanium dioxide photocatalysis with focus on mechanims, synthesis, and applications. Synthetic methods include sol-gel, sonochemical, microwave, oxidation, deposition, hydro/solvothermal, and biological techniques. Applications comprise the production of energy, petroleum recovery, and the removal of microplastics, pharmaceuticals, metals, dyes, pesticides, and of viruses such as the severe acute respiratory syndrome coronavirus 2.

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