The early evaluation of this joint and the collaborative work of odontologists and rheumatologists are both necessary for a better management of TMJ pathologies.

Rheumatoid nodulosis is an entity that describes a particular variant of polyarthritis associated with early manifestations of palindromic rheumatism, radiologic subchondral bone cysts, and subcutaneous rheumatoid nodules. This study describes the clinical, radiologic, histologic, crystallographic, and laboratory findings, as well as the outcome in a group of 16 patients with rheumatoid nodulosis that were followed for a period of 1-12 years. Six of these patients had an aggressive course and developed classic erosive polyarticular rheumatoid arthritis, while the others continued having episodic arthritis without erosive disease. Seven patients had cholesterol crystals in olecranon bursae containing nodules. Second-line drugs used to control the articular manifestations did not improve the nodulosis, erosive, or cystic subchondral bone changes. Rheumatoid nodulosis mimics several other rheumatic diseases, and in about 40%, classic erosive rheumatoid arthritis develops. The presence of cholesterol crystals in rheumatoid nodules or affected bursae can increase the confusion with other crystal-induced arthritis, in particular, tophaceous monosodium urate gout or xanthomatosis.

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Background Coeliac disease (CD) is an autoimmune disease caused by exposure to gluten in genetically predisposed individuals. The detection of anti-transglutaminase IgA (tTG) and anti-endomysial (EMA) is used for screening of CD with sensitivity and specificity of 90% and 99%. The association between CD and connective tissue diseases (CTD) has been reported. Objectives The objective was to describe the frequency of IgA tTG and EMA in patients with definite diagnosis of CTD and inflammatory arthropathies (IA). Methods Patients ≥18 years with CTD and IA were included. Values of ≥20 for tTG (ELISA) and ≥10 for EMA (IIF) were considered positive. Medium were used for numeric variables and interquartile percentages for categorical variables. Confidence intervals were calculated for 95%. Results Of 149 patients with various diagnoses included, 8 had at least one positive antibody (5.37% CI =1.75-8.99), 6 had both (4.03% CI =0.87-7,18) and 2 had only tTG. Eight patients were diagnosed with CD and biopsy was performed in 4 (see table below). In this study 5.37% presented positive serology for CD. Positive antibodies were found in patients with Sjögren's syndrome, rheumatoid arthritis, psoriatic arthritis, polymyositis and lupus, as reported by other authors. Table 1. Clinical characteristics of patients with positive antibodies for coeliac disease (n=8) n Age Sex CTD CD manifestations Anemia Anti-tTG EMA Biopsy 1 37 F SLE No Yes + + + 2 42 F SLE No Yes + + + 3 58 F PM No Yes + + + 4 49 F SS Si Yes + + + 5 71 M APS No No + − ND 6 55 F IA No Yes + + ND 7 34 F RA No Yes + − ND 8 42 F RA No Yes + + ND Conclusions According to our findings, it would be useful to perform a serological screening for CD in CTD, due to the overlap of autoimmune diseases, as well as in undifferentiated arthritis, to determine in those patients in whom the small bowel biopsy should be performed for definitive diagnosis. References Gόmez JC, Selvaggio GS, Viola M, Pizarro B, La Motta G, de Barrio S et al. Prevalence of celiac disease in Argentina: screening of an adult population in the La Plata area. Am J Gastroenterol 2001; 96: 2700-4. Luft LM, Barr SG, Martin LO, Chan EK, Fritzler MJ. Autoantibodies to tissue transglutaminase in Sjögren's syndrome and related rheumatic diseases. J Rheumatol 2003; 30:2613-9. Koehne Vde B, Bahia M, Lanna CC, Pinto MR, Bambirra EA, Cunha AS. Prevalence of serological markers for celiac disease (IgA and IgG class antigliadin antibodies and IgA class antiendomysium antibodies) in patients with autoimmune rheumatologic diseases in Belo Horizonte, MG, Brazil.Arq Gastroenterol; 2010; 47:250-6. Disclosure of Interest : None declared DOI 10.1136/annrheumdis-2014-eular.2624