DOLESCENT DEPRESSION IS A common, chronic, recurrent, and impairing condition that accounts for a substantial proportion of the disability and mortality incurred in this age group. 1,2 Untreated depression results in impairment in school, interpersonal relationships, occupational adjustment, and in

Fluoxetine was superior to placebo in the acute phase treatment of major depressive disorder in child and adolescent outpatients with severe, persistent depression. Complete remission of symptoms was rare.

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