Background: Consumption of nutrients such as docosahexaenoic acid (DHA), prebiotics, and beta‐glucan have been associated with a decrease in the occurrence of allergic manifestations (AM). Objective: To assess if consumption of a follow‐up formula with these and other essential nutrients would affect incidence of AM in children. Methods: In this double‐blind, randomized, controlled trial, healthy 1‐4 year old children from 2 daycare centers in Brazil were fed 3 servings/day of a cow’s milk‐based follow‐up formula with DHA, prebiotics polydextrose (PDX) and galactooligosaccharides (GOS), and beta‐glucan (FF; n=125), or an unfortified cow’s milk‐based beverage (C; n=131) for up to 28 weeks. Occurrence of AM was assessed by study pediatricians and analyzed by the Cochran‐Mantel‐Haenszel test and the counting process of Andersen‐Gill. Results: The FF group had fewer episodes of AM, which included allergic rhinitis, conjunctivitis, wheezing, allergic cough, eczema, and urticaria (Table) and a lower hazard ratio for having AM (HR, 0.64; 95% CI 0.47‐0.89; p=0.007). Conclusions: A cow’s milk‐based formula with added DHA, PDX, GOS, and beta‐glucan and fortified with micronutrients including zinc, vitamin A, and iron, when consumed 3 times per day for 28 weeks by 1‐4 year old children, was associated with fewer allergic manifestations in the skin and the respiratory tract.

Fermentação alcoólica de melaço com alta concentração de açúcar: efeito da esterilização do mosto e tratamento ácido da levedura Graziele Bortolozzo Cabral Dissertação apresentada para obtenção do título de Mestra em Ciências. Área de concentração: Ciências e Tecnologia de Alimentos Piracicaba 2020 Graziele Bortolozzo Cabral Engenheira de Alimentos Fermentação alcoólica de melaço com alta concentração de açúcar: efeito da esterilização do mosto e tratamento ácido da levedura versão revisada de acordo com a resolução CoPGr 6018 de 2011