The main limiting factor in patient retention was adverse drug reactions. Patients taking lamotrigine (LTG) or gabapentin (GBP) did better than those taking carbamazepine. Seizure control was similar among groups. LTG and GBP should be considered as initial therapy for older patients with newly diagnosed seizures.
tient selection criteria for this important trial, which could eventually offer another treatment option for patients with aggressive forms of MS previously resistant to more conventional forms of disease-modifying therapy. If the past is a pre-dictor of the future, AHSCT may provide a viable treatment option for patients with RRMS with aggressive breakthrough disease, as well as selected patients with progressive forms of the disease.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.