Determination of TiOCl2 in refined TiCl4 was significant for analysis of its impurities. TiOCl2 could be determined by infrared spectroscopy due to its infrared characteristic spectrum line. However, normal infrared absorption cell was not fit for the sample analysis, because TiCl4 easily reacted with moisture in the air and immediately was hydrolyzed to form highly corrosive hydrochloric acid smoke. The infrared absorption cell with the window film of ZnSe ( Ф10×1mm, wavenumbers: 7800cm-1~440cm-1) and the glass cell (optical path: 22mm, 12mm, 7mm and 4mm) was assembled and utilized in determination of the TiOCl2 in refined TiCl4 by standard addition method. The detection limit of TiOCl2 was 26.5mg•kg-1, the regression equation was Y=1.0118X, R2=0.9926; With standard addition method, the regression equation of TiOCl2 was Y=1.9400X, R2=0.9940,This infrared absorption device was safe, simple and convenient, easily removable and washable, and re-useable. This method could meet the requirement of determination of TiOCl2 in refined TiCl4.