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A diagnosis of hepatic steatosis is related to an increased risk of CKD among non-alcoholic and non-diabetic Chinese adults regardless of whether the diagnosis was acquired via ultrasound, CAP or FLI. Increased hepatic lipid content may contribute to CKD development.

The aim of this studyThe aim of this study was to verify whether prohibitin is a novel autoantigen in rheumatoid arthritis.Material and methodsFirst, recombinant human prohibitin (rhPHB) protein was cloned, expressed, and purified. Then the anti-prohibitin autoantibodies were detected by western blotting by using rhPHB protein to incubate sera from patients with rheumatoid arthritis (RA). Next, immunoprecipitation was employed to further illustrate whether anti-prohibitin antibodies exist in RA patients. And finally, autoantibodies against the rhPHB protein were investigated using a homemade ELISA kit through the assessment of 258 real clinical samples.ResultsIt was revealed that anti-prohibitin antibodies existed in the sera of patients with RA. Reactivity of serum IgG against rhPHB was detected in 26 of 86 RA patients (30.3%), 7 of 86 systemic lupus erythematosus (SLE) patients (8.1%), and 1 of 86 apparently healthy donors (HC) (1.2%).ConclusionsProhibitin was proved to be a novel autoantigen and the corresponding anti-prohibitin autoantibodies were present in the RA patients' blood circulation.

This paper conducts a systematic review of articles on trust in government and rumor-related behavior published during the Covid-19 pandemic (2020-2022). This systematic review seeks to answer two questions: first, whether there is a link between trust in government and rumor-related behavior; and second, whether there are any recommendations for the government to reduce the negative impact of rumors and improve government reputation. According to the PRISMA guideline, we chose 11 articles for discussion from the Scopus, PubMed, and Web of Science databases. According to the findings, increased trust in government can promote positive health behaviors. Furthermore, we found some suggestions for the government to reduce the negative impact of rumors while maintaining trust levels.