Adenoid cystic carcinoma (ACC) of the breast is very rare in males. There have been only eight previous articles published on breast ACC in males. Here, we will report on the first case of this type of tumor in the Chinese province of Hainan. The patient was a 19-year-old male, and he underwent a radical mastectomy (RM) with axillary lymph node dissection. The histopathological examination specimen revealed that surgical margins were negative; none of the 41 axillary lymph nodes excised were positive for malignancy. The patient is alive and well 67 months after radical mastectomy. In the present study, we discuss the diagnosis and treatment options for male breast ACC based on previous English publications.Electronic supplementary materialThe online version of this article (doi:10.1186/s12957-015-0442-8) contains supplementary material, which is available to authorized users.

Secretory breast carcinoma (SBC) is a rare tumor that is particularly rare in male adults. To our knowledge, only 28 previous male cases of secretory breast carcinoma have been reported. The present a case of secretory breast carcinoma has the longest symptom duration of (40 years) in a male individual until now. Typically, the clinical features and treatment of male SBC are similar with female SBC. The ETV6-NTRK3 fusion gene is a specific genetic alteration in SBC. When compared to other types of male breast cancer, patients with male secretory breast cancer are much younger, and have a lower rate of estrogen/progesterone hormone receptor positivity. Modified radical mastectomy has been favored as a therapeutic approach in all female SBC, male SBC and other types of male breast cancer. [corrected].

The ultraviolet (UV)/H2O2, UV/O3, UV/peroxodisulfate (PDS) and UV/peroxymonosulfate (PMS) methods are called UV-based advanced oxidation processes. In the UV/H2O2 and UV/O3 processes, the free radicals generated are hydroxyl radicals (•OH), while in the UV/PDS and UV/PMS processes, sulfate radicals (SO4•−) predominate, accompanied by •OH. SO4•− are considered to be more advantageous than •OH in degrading organic substances, so the researches on activation of PDS and PMS have become a hot spot in recent years. Especially the utilization of UV-activated PDS and PMS in removing antibiotics in water has received much attention. Some influencing factors and mechanisms are constantly investigated and discussed in the UV/PDS and UV/PMS systems toward antibiotics degradation. However, a systematic review about UV/PDS and UV/PMS in eliminating antibiotics is lacking up to now. Therefore, this review is intended to present the properties of UV sources, antibiotics, and PDS (PMS), to discuss the application of UV/PDS (PMS) in degrading antibiotics from the aspects of effect, influencing factors and mechanism, and to analyze and propose future research directions.

Rationale: Triple or more primary malignancies are rare, with only 23 previous cases including breast cancer reported in the English language studies between January 1990 and December 2019. Patient concerns: The patient was a 67-year-old woman with a mass in her right breast. She had a previous history of uterine and colon cancer. Both ultrasonography and mammography revealed a Breast Imaging Reporting and Data System (BI-RADS) category 3 breast lesion, in which proliferative nodules are more likely. Given her previous history of 2 malignancies, her doctors strongly recommended a biopsy. Diagnosis and interventions: The biopsy pathology suggested intraductal breast cancer. Mastectomy and sentinel lymph node biopsy were performed. The postoperative pathological diagnosis was invasive ductal carcinoma, grade II, stage I. The sample was positive for estrogen receptor and progesterone receptor and negative for cerbB-2. No radiotherapy or chemotherapy was administered except for endocrine therapy. A follow-up at 19 months showed no breast recurrence or distant metastases. Outcomes: No recurrence or distant metastasis occurred within the 19-month, 11-year, and 20-year follow-ups for breast, colon, and uterine cancers, respectively. Lessons: To our knowledge, this is the first review of triple or more primary malignancies including breast cancer. These malignancies occur predominantly in older female patients. The most prevalent tumors of triple or more primary malignancies including breast cancer occur in the colon, uterus, and lung. A favorable prognosis is associated with early-stage malignancies.