Breast density does not impact overall CAD detection of breast cancer. There is no statistically significant difference in breast cancer detection in dense and nondense breasts. However, the detection of breast cancer manifesting as masses is impacted by breast density. The false-positive rate is lower in nondense versus dense breasts. CAD may be particularly advantageous in patients with dense breasts, in which mammography is most challenging.

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Introduction: Although studies have examined emergent CTAs of the head and neck in patients seen by neurologists who are suspected of having a large vessel occlusion, the utility and accuracy of CTA for patients called as a ‘code stroke’ by any healthcare provider has not been evaluated. Methods: At our institution, imaging for all Code Stroke patients includes non-contrast CT of the brain as well as CTA of the neck and brain, regardless of severity. This imaging is often performed prior to detailed neurology evaluation. We queried our radiology department report database for all studies labelled ‘CTA ELVO’, an imaging order code which is specific for Code Stroke. We then cross-referenced this list with our prospectively acquired ischemic stroke registry, which consists of all patients discharged with a diagnosis of acute ischemic stroke. Results: Between January and August 2017, 1265 CTA ELVOs were performed. Average age was 66.3 years, and 52.4% were female. Of all CTA ELVOs, 144 were performed on inpatients (11.3%) and neuroradiologists read 149 studies (11.8%). Critical findings on vessel imaging were present in 165 studies (13%); of these 118 patients were ultimately diagnosed with acute ischemic stroke. Studies with critical findings involved older patients (73.7 years, p<0.001) and were less likely to be performed on inpatients (29 studies, p=0.012) but were no different in number of females (55%, p=0.51) or whether read by a neuroradiologist (23 studies, p=0.36). Critical findings included acute intracranial large vessel occlusion involving the middle cerebral artery, intracranial internal carotid artery (ICA), or basilar artery (87 studies); critical cervical ICA stenosis, acute cervical ICA occlusion, or acute dissection (42 studies); M2 occlusion (32 studies); critical intracranial stenosis (7 studies) and vascular malformation such as aneurysm or arteriovenous malformation (6 studies). Conclusion: The yield of non-invasive vessel imaging in patients called as a code stroke in detecting critical findings is high, revealing abnormalities in approximately one in eight patients. Patients presenting with acute neurologic symptoms should receive vessel imaging as part of the initial workup for suspected stroke.