In the unusual 2020, how to manage trauma under the pandemic of COIVD-19 is a hot topic worldwide. Because the high mortality led by severe traumatic haemorrhage, hemostasis and trauma-induced coagulopathy are the important concerns in trauma treatment. As we known, trauma is the leading cause of death in people under age of 44 years, which has attracted great attention from the field, but trauma in special population, such as elderly people and people who take anticoagulant drugs, was less to discuss. Sepsis is another topic can’t be ignored when we talking about trauma, it is also believed has some relation with the mortality caused by COIVD-19 infection. Any progress in trauma based on the new discoveries in the related basic research, however, there is no any breakthrough in this year. This article reviewed the recent literatures on these hot topics in trauma, and try to give some new angles to study in this field.