Background: Urinary tract infection (UTI) is one of the most important causes of bacterial infections across the globe. Increasing antibiotic resistance among urinary pathogens to commonly prescribed drugs has become a therapeutic challenge. Periodic evaluation of antimicrobial activity of different antibiotics is essential as the pattern of antibiotic sensitivity may vary over periods.Methods: This cross-sectional study was undertaken in the Department of Medicine, Sylhet MAG Osmani Medical College, Sylhet from January 2019 to June 2019 among 100 adult patients admitted Medicine indoor Department confirmed as UTI on the basis of symptoms, signs and compatible investigation, urine culture either positive or negative.Results: Out of the total 100 urine samples 60 samples were positive for pathogenic organisms. Escherichia coli was isolated in 41 (68.3%) of the positive samples, followed by Klebsiella sp 13 (21.6%), Pseudomonas sp 3 (5%) Proteus sp 2 (3.3%) staph. Aureus 1 (1.66%). E coli was found to be most sensitive to nitrofurantoin (92.5%), meropenem (92.5%), amikacin (84.6%) and gentamycin (71.8%) and resistant to most commonly used drugs like cefixime (78%), cefuroxime (77.5%), ciprofloxacin (62.5%), ceftriaxone (62.5%).Conclusions: Mainly gram-negative bacilli are found to be responsible for UTI and most frequent isolated bacteria was E-coli. The most sensitive antibiotics were nitrofurantoin, meropenem, and amikacin& gentamycin. Frequently usedantibiotic like cefixime, cefuroxime, cotrimoxazole, ciprofloxacin & ceftriaxone were mostly resistant to E-coli.

Introduction: Urinary tract infections (UTIs) encompass a wide array of infections, accounting for a vast number of community as well as hospital acquired infections. This study was undertaken to evaluate the clinical presentations and bacteriological profile of UTI patients in indoor setting. Methods: This 6 months cross-sectional study enrolled 100 patients admitted in Medicine department of Sylhet MAG Osmani Medical College Hospital with symptoms and signs of UTI subsequently confirmed by compatible investigations including urine culture. Results: Among 100 patients of UTI, maximum were females (67%) and the male female ratio was 0.49: 1. The most common age group was 46–60 years (34%). Majority (68%) of the patients had upper UTI while lower UTI constitutes 32%.66% of the patients had complicated while 34% have uncomplicated UTI.18% of the patients had recurrent UTI. Most of the patients had fever (55%), followed by loin pain (37%) as their presenting symptoms. The most common risk factor was loss of host defense 38% (diabetes mellitus/ use of immunosuppressive drugs).Out of 100, 60 urine samples were positive for pathogenic organisms. Escherichia coli was isolated in 41 (68.3%) of the positive samples, followed by Klebsiella sp 13 (21.6%), Pseudomonas sp 3 (5%) Proteus sp 2 (3.3%) Staph. Aureus 1(1.66%). Conclusion: The most common clinical presentations of UTI in admitted UTI patients are fever and loin pain. Diabetes mellitus is the most important risk factor. Mainly Gram negative bacilli were found to be responsible for UTI and most frequent isolated bacteria was E-coli. J Bangladesh Coll Phys Surg 2021; 39(2): 106-113