The tourism industry has been one of the fastest growing sectors of the world economy since the second half of the 20th century. Along with the COVID-19 global crisis, the sector has suffered a great destruction in a process where the tourism sector is gaining momentum. This chapter was carried out on the measurement and management of the economic effects of the COVID-19 global crisis on the tourism sector. A survey was conducted with 322 participants working as managers in different units in various travel agencies operating in Turkey. The construct validity of the scales was carried out by exploratory factor analysis. In the chapter, it was seen that crisis management practices were gathered under four dimensions. In results of the data, the total variance explanation rate for the marketing factor was 57.291%, for the human resources was 10.132%, for the government support was 7.937%, and for the maintenance was 5.286%.