No abstract

No abstract

H-'H coupling pattern may not be resolved, precluding the use of this method for assigning sugar pucker. Clearly, the 'H and 13C methods are complementary and both can be very useful. Finally, l3C signals are useful in defining metal-binding sites. The same advantages of this method for mononucleotide studies are passed on to oligonucleotide studies.25 Signals for carbons remote from the metal binding site appear to be most useful. discussions with Prof. David Live.

We report in this communication the first example of catalytic alkyne metathesis reactions mediated by well-defined non-d 0 alkylidyne complexes. The air-stable d 2 Re(V) alkylidyne complex Re4, bearing two PO-chelating ligands and a labile pyridine ligand, could catalyze homometathesis of internal alkynes with a broad substrate scope, including alcohols, amines, and even carboxylic acids. The catalyst can tolerate heating, air, and moisture in both solid and solution states, and the catalytic metathesis reactions could proceed normally in wet solvents.