The aim of the present study was to investigate the clinical effects of Shengxuening tablet (silkworm excrement) combined with recombinant human erythropoietin (rHuEPO) for the treatment of renal anemia of maintenance hemodialysis (MHD) patients. Seventy-two MHD patients with renal anemia were included in the study and randomly divided into the control (n=34) and observation (n=38) groups. Patients in the control group were treated by hypodermic injection of 100–150 U/(kg·w) rHuEPO and patients in the observation group were treated by rHuEPO + 1.0 g t.i.d. p.o. Shengxuening tablet. The two groups were assisted by conventional treatments including iron, folic acid, vitamin B12 and L-carnitine. After 3 and 6 months, improvement of anemia was compared. After 3 months, the hemoglobin, hematocrit, serum ferritin and transferrin saturation levels of the observation group were significantly higher than those of the control group (p<0.05). In addition, C-reactive protein and superoxide dismutase levels of the observation group were significantly lower than those of the control group (p<0.05). After 6 months, indices of the observation group were ameliorated while the improvement of control group was not obvious, and indices of the observation group were significantly higher than those of the control group (p<0.05). Consumption of rHuEPO in the observation group was significantly less than that of the control group, and the total effective rate was significantly higher than that of the control group (p<0.05). In conclusion, Shengxuening tablet combined with rHuEPO was safe and effective for the treatment of renal anemia of MHD patients.

Background Shoulder arthroscopic surgery has become the first choice for the surgical treatment of a variety of shoulder diseases. In previous studies, the incidence of hypoxemia after shoulder arthroscopic surgery was 12.6% and 16%, which is usually accompanied by several unfavourable consequences, including prolonged ventilator support, increased hospital length of stay, increased intensive care unit length of stay, and higher perioperative mortality. The Purpose of this study is to identify independent risk factors of postoperative hypoxemia in the post anesthesia care unit(PACU)after shoulder arthroscopic surgery. Methods This was a single-center retrospective study including 358 patients undergoing shoulder arthroscopic surgery between January 2020 and January 2021 at LuoYang Orthopedic Hospital of Henan Province Orthopedic Hospital of Henan Province. The relative factors of postoperative hypoxemia were tested through descriptive analysis and logistic regression, and the independent risk factors were obtained. Results The incidence of postoperative hypoxemia was 14.0% in our study. Through descriptive analysis and logistic regression, the independent risk factors of postoperative hypoxemia were as follows: age[odd ratio(OR)=1.069, 95% confidence interval (CI) = 1.012–1.129,P = 0.018]、body mass index (BMI) (OR = 1.425,95% CI = 1.250–1.626,P = 0.000、operating time (OR = 1.011,95%CI = 1.000-1.021,P = 0.041) irrigation fluid volume (OR = 1.093,95%CI 1.033–1.156,P = 0.002) . Conclusion Age, BMI, operating time, irrigation fluid volume were 4 independent risk factors for postoperative hypoxemia in the PACU after shoulder arthroscopic surgery.