Background Zinc finger proteins encompass one of the unique and large families of proteins with diversified biological functions in the human body. These proteins are primarily considered to be DNA binding transcription factors; however, owing to the diverse array of zinc-finger domains, they are able to interact with molecules other than DNA like RNA, proteins, lipids and PAR (poly-ADP-ribose). Evidences from recent scientific studies have provided an insight into the potential functions of zinc finger proteins in immune system regulation both at the transcriptional and post transcriptional level. However, the mechanism and importance of zinc finger proteins in the regulation of immune response is not very well defined and understood. This review highlights in detail the importance of zinc finger proteins in the regulation of immune system at transcriptional and post transcriptional level. Conclusion Different types of zinc finger proteins are involved in immune system regulation and their mechanism of regulation is discussed herewith.

Abscisic acid (ABA) is a key plant growth and stress hormone involved in many biological processes. It has been shown to be involved in Reactive Oxygen Species (ROS) generation. Class-III Peroxidases (PODs) are known to maintain oxidative stress induced-ROS at sublethal levels in plants under abiotic stress conditions, but, studies documenting how ABA regulates boiling stable class-III PODs are still a matter of conjuncture. In this study, the ABA-induced changes on ROS and ROS scavenging class III boiling stable POD were studied in the embryos of different cultivars of wheat. Simultaneous analysis of ROS contents, activities of ROS-scavenging class-III boiling stable POD enzymes gave an integrative view of physiological state and detoxifying potential under conditions of sensitivity and tolerance. Indices of oxidative stress viz., superoxide radical and H2O2 content increased under ABA treatment in a genotype dependent manner. It was observed that cultivars: PBW 550, HD 2967 and PBW 621 have more efficient mechanism to scavenge ROS species as shown by increase in BsPOD activity accompanied by enhanced expression of boiling stable POD isoenzymes. Based on results it can be inferred that embryos of cvs. PBW 550, HD 2967 and PBW 621 have more capacity to perform biological antioxidative reactions to combat ABA-induced oxidative stress.

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