Benign (Jessners) lymphocytic infiltration of the skin is a chronic, benign T-cell infiltrative disorder, usually manifesting as erythematous papules or plaques on the face, neck and back. We report the case of a 30-year -old female, who presented with erythematous papules and plaques on face, upper back, front of chest, of 4 months duration and erythematous plaque on both dorsa of hand and Fore arms of 1 month duration. Skin biopsy confirmed the diagnosis of jessner's lymphocytic infiltration of the skin. The evolution was favorable with hydroxy chloroquine.

The object of our study is to know the incidence of gonorrhea in reproductive age group women suffering with leucorrhoea attending STI Clinic in King George Hospital in Visakhapatnam. MATERIAL AND METHODSIn our present study, we included 120 female patients of reproductive age group women (20-45 years) with leucorrhoea attending STI Clinic; we also examined the male partners. The diagnosis of Gonorrhoea is confirmed by smear and culture examination. The vaginal discharge was collected with sterile swabs and inoculated in modified Thayer-Martin media for 48-72 hours. Gram staining was done to examine the smear under microscope to examine the diplococci. Urethral and rectal swabs collected from their male sexual partners and sent for smear and culture. RESULTSIn our study, results shows women suffering with Gonococcal infection and some percent of male partners suffering with Gonococcal infection and it shows the transmission occurs predominantly through sexual contact are asymptomatic carriers and source of infection to their male partners. We found Gonorrhoea is the common cause of Leucorrhoea next to Candidiasis and Trichomoniasis. CONCLUSIONTreatment of both male and female sexual partners is essential to control and prevent the recurrence of Gonorrhoea. Early diagnosis and treatment of Gonorrhoea in female patients will prevent late complications like PID, tubal block, ectopic pregnancy and sterility in reproductive age group women.

Jessners lymphocytic infiltration of the skin is a chronic, benign T-cell infiltrative disorder, usually manifesting as erythematous papules or plaques on the face, neck and back. we report the case of a 66-year -old man, who presented with erythematous papules and plaques on nose of 4 months duration and erythematous plaque on right arm of 1 month duration. skin biopsy confirmed the diagnosis of jessner's lymphocytic infiltration of the skin.The evolution was favorable with hydroxy chloroquine and prednisolone. KEYWORDS: Jessners lymphocytic infiltration of skin, hydroxy chloroquine and Prednisolone. INTRODUCTION:Jessner's lymphocytic infiltration of the skin (JLIS) is a skin condition of unknown aetiology characterized by erythematous papules and plaques located on the head, neck and upper back. The eruption resolves spontaneously after months or a few years but can recur for several years. A variety of empirical treatments has been tried with limited success. Here we report a case of jessners lymphocytic infiltration of skin successfully treated with hydroxychloroquine and prednisolone.

BACKGROUND:Lichen planus is a chronic inflammatory disease that effects skin, mucous membranes, hair and nails. There are several drugs both topical and systemic for the treatment of lichen planus. AIMS AND OBJECTIVES: Present study was done to compare the efficacy between oral mini pulse therapy with betamethasone and with acetretin in the management of generalised lichen planus. MATERIALS AND METHODS: The study was carried out on patients who were clinically diagnosed as generalised lichen planus, attending the outpatient department of dermatology, venereology and leprosy, King George hospital, affiliated to Andhra medical college, Vishakhapatnam from November 2011 to December 2012. A total of 60 patients were included in study and divided into two equal groups. Group1 patients were treated with 0.1mg/kg of oral betamethasone given on 2 consecutive days in a week till 8 weeks and tapered. Group 2 patients were treated with 0.5mg/kg of acetretin for 8 weeks and tapered. INCLUSION CRITERIA: All patients of age group in between 11-60 years, of either sex, suffering from lichen planus of duration >3 months, and women in group 2 who were in reproductive age group on two methods of contraception were included. EXCLUSION CRITERIA: Pregnant and lactating women, in Group 1: patients suffering from diabetes, hypertension, peptic ulcer disease, renal, hepatic, heart disease or tuberculosis, in Group 2: patients with abnormal lipid profile, diabetes, hypertension, renal, liver or heart disease were excluded. RESULTS: out of 60 patients enrolled in study, 2 patients from group 1 and 5 patients from group 2 were dropped from study and results were concluded. Majority of patients were in age group of 31-60 (78.3%) with male to female ratio of 2.1:1.Group 1 patients at the end of 8 weeks response was seen in 92.8%, with relapse rate of 15.38% after 6 months of follow up. Group 2 patients at end of 8 weeks response was seen in 72 % with relapse rate of 5.5%. CONCLUSION: In our study oral mini pulse therapy with betamethasone has early onset of action and with a complete response in majority of patients with slightly more relapse rate when compared to oral acetretin. Oral acetretin has less relapse rate due to prolonged half-life.

Pyoderma gangrenosum (PG) is a chronic, painful ulcerated skin disease of unknown etiology. Its association with inflammatory bowel disease like ulcerative colitis is common. The lesions generally appear during the course of active bowel disease, frequently concur with exacerbations of colitis, sometimes with inactive ulcerative colitis. 15 to 20 % of patients with Pyoderma gangrenosum have ulcerative colitis and 0.5 to 5 % of patients with ulcerative colitis have Pyoderma gangrenosum. occasionally skin lesions may preceed active inflammation of colon. Here we report a case of 50 year old female presenting with large ulcerated lesion over the anterior aspect of the middle 1/3 rd of left leg associated with severe pain and bloody discharge. skin biopsy shows epidermis with necrosis and diffuse dense neutrophilic infiltrate in superficial epidermis extending into the deep dermis. Colonoscopy shows features of ulcerative colitis. Patient showed rapid response with systemic steroids and specific treatment with 5-amino salicylic acid (mesalamine). ulcer healed within 6 weeks and followed for 3months with no recurrence.