Objective: This study was conducted to generate the data on drug utilization pattern among geriatric inpatients in general medicine department. Methods:The patient's prescriptions and medical record files were randomly selected on the basis of inclusion and exclusion criteria at medicine department of Shri Mahant Indiresh Hospital, Dehradun and the required data for the study were collected in well-designed data collection form and evaluated after the period of 3 mo. Results:Conclusion: Most of the drugs were utilized by male patients and the rate of polypharmacy was high.Among 175 patients, males were predominant and 31.42% patients were in age group of 71-75 y. Cardiovascular diseases (28%) were most common cause of hospitalization followed by, respiratory disorders (20.57%). Hypertension (25.72%) was most commonly diagnosed disease followed by, diabetes mellitus (22.2%) and chronic obstructive pulmonary disease (14.28%). The most common comorbidity was hypertension and diabetes mellitus. More than 3 co-morbidities were found in 79 patients. Cardiovascular drugs (22.17%) was most frequently prescribed drug followed by, gastrointestinal drugs (15.30%). Among individual drugs pantoprazole (A02BC02) was most commonly prescribed drugs. Total of 1581 drugs was prescribed with an average of 9.03 drugs per prescription. Only 9.63% drugs were prescribed by generic name. Antimicrobials were prescribed in 146 prescriptions, among them ceftriaxone (J01DD04) was frequently prescribed.

The liver plays vital functions in maintaining, performing and regulating the homeostasis of body and it involves in almost all biochemical pathways such as nutrient supply, reproduction, biotransformation, energy supply and growth. The liver metabolize, detoxify and activate exogenous as well as endogenous compound and is capable for transforming foreign chemicals as it has high level of enzymatic system. Liver disorder or injury is defined as conditions, diseases, or infections that influence the structure and/or function of