The use of biological pesticides for protecting plants from various infectious diseases and controlling abiotic stresses is becoming increasingly widespread in various agricultural crops. However, the effectiveness of biological plant protection is strongly dependent on various factors, in particular on weather conditions. To increase the impact of the use of biological products in plant protection against diseases, it is necessary to search for new approaches. One of the ways to increase the return on the use of biological products is the use of special adaptogens that increase the resistance of biological agents of biopesticides to the negative influence of the external environment. The Kazan State Agrarian University developed an adaptogen for bioagents of biological products based on alcohol extracts of millet. In 2019, on spring barley, the use of their mixtures with an adaptogen when spraying with biological products made it possible to increase the yield per 1,75 t / ha in comparison with the control and per 0,36 t / ha when using only biological products. At the same time, the effectiveness of control of the main leaf mycoses increased. In 2020, studies were carried out to evaluate the effectiveness of the use of biological products with the addition of the silicon-containing mineral diatomite when spraying barley plants. It has been established that the use of such formulations makes it possible to increase the productivity of plants, enhance the effectiveness of pathogen control in comparison with a standard biofungicide