227ChemInform Abstract The title compound reacts with various α,β-bifunctional compounds to give rise to formation of heterobicyclic systems in good to excellent yields. The factors which affect the cyclization are dependent on the cyclizing agent as well as on the nature of the side chain group present in the parent compound.

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Background: The advantage of Ozaki technique for aortic valve replacement surgery over the conventional approach is still debated. This study aimed to evaluate early outcomes after aortic valve replacement using the Ozaki technique Methods: We prospectively included 20 patients who had aortic valve replacement May 2018 to June 2020. Postoperative bleeding, mechanical ventilation, ICU stay and echocardiographic outcomes were observed. Results: The mean age was 39.9±14.8 (20-69) years.13 patient had aortic regurge while 7 had aortic stenosis. Aortic cross-clamp (76.2±8.5 (60-100) and cardiopulmonary bypass times (103.8±15.3 (80-125).One patient (5%) was converted to aortic valve replacement by mechanical valve due to significant aortic regurge. Neither significant gradient nor regurge was found on one month follow-up echography. Freedom from infective endocarditis was found in all patients. No significant difference was found in the ejection fraction pre and post-operative. Conclusion: This novel technique seems to have a promising and favorable outcome with no need for anticoagulation and lesser post-operative complication compared to ordinary aortic valve replacement. This technique is associated with low mortality and morbidity.

The action of phenylmagnesium bromide on 6‐p‐chlorostyryl‐3‐thioxo‐1,2,4‐triazin‐5‐one (1) was studied whereby a mixture of seven products was obtained. These were separated and characterised, and a reasonable mechanism for their formation is presented and discussed.

In Fortführung früherer Untersuchungen werden die Reaktionen der Titelverbindungen (Ia) und (Ib) mit einer Reihe von Verbindungen untersucht und die Strukturen der Produkte anhand ihrer IR‐Spektren abgeleitet.