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Despite numerous observations and publications on the aethiology and pathogenesis of chronic gastritis many questions remain unanswered (1,2,3,4,6). Views on the aethiolcgy of chronic gastritis changed when in 1982 Campylobacter pyloridis (later named Campylobacter pylori CP) was first isolated in Western Australia from the stomach of patients with gastritis lesions and peptic ulceration (5).The aim of this study, carried out with cooperation with gastroenterologist, has been to investigate the ultrastructural changes in gastric surface epithelium and lamina propria in selected patients endoscopicaUy diagnosed gastritis.Observations have been carried out on 20 patients (10 men and 10 women). Biopsy material was obtained during endoscopy. In cases when the presence of bacteria has been confirmed further E M investigations have been introduced. Semithin sections for LM observations and ultrathin sections for EM were prepared according to routine EM technique.CP was found both on the airface of gastric epithelium cells, and what has not been reported so far, inside the lumen of the fundic glands (Fig. 1).

A cytochemical study on the nuclei of hepatocytes in the regenerating liver after partial hepatectomy by the method of Higgins and Anderson was carried out. The behaviour of the ribonucleoprotein components of the nucleus, using EDTA according to Bernhard, revealed altered proportions of the fibrillar and granular components of the nucleoli in the early phase of regeneration and morphologic changes in nuclear RNP, especially in perichromatin fibrils. At 6 h after hepatectomy, the reaction with perichromatin fibrils (FP) was intense, localized around fields of condensed chromatin, which suggests intense transcription of extranucleolar RNA. The behaviour of the remaining nuclear ribonucleoproteins was uncharacteristic.

Cytochemical study of hepatocytes nuclei of the liver irradiated with a dose of 650 rad and irradiated after partial hepatectomy was performed. Morphological exponents of the intensive synthesis of preribosomal RNA in the nucleolus, as well as the transcription of heterogeneous RNA contained in perichromatin fibrils were revealed under the ionizing radiation effect. The behavior of perichromatin granules in the course of the experiment suggests delay in the transport of messenger RNA to cytoplasm, influenced by gamma radiation. Nuclear bodies were observed very often in nuclei of hepatocytes of irradiated animals.