No abstract

No abstract

5-Aminopyrimidine gives, on mild heating with lV-alkyl(aryl)imidoyl chlorides in the presence of phosphorus oxychloride, 4-formyl-l,2-dialkyl(aryl)imidazoles together with the 7V-(pyrimidin-5-yl)-7V-alkyl(aryl)amidines. It was found that these amidines are the precursors of the imidazoles. This new rearrangement reaction of the pyrimidine ring takes place by attack of the nucleophilic end of the side chain at position 5 of the pyrimidine ring on C(6).

No abstract

No abstract