Due to increased longevity and awareness, most women seek help of the clinicians for these symptoms. Estrogen therapy has been recommended to postmenopausal women for alleviation of symptoms and long-term benefits (3).However, recent evidence from studies of Women's Health Initiative showed that the combined estrogen and progestin therapy increased risks of coronary heart disease, stroke, pulmonary embolism and breast cancer (4). Recently, estrogen-like compounds from plants like soy proteins provide a new nutritional dimension to the management of short-term as well as long term effects of estrogen deficit (5). Epidemiological data suggest and indicate that only 25% of Japanese women complain of climacteric symptoms compared with 85% North American women and this difference has been attributed to soy protein consumption in Asian countries (6).The beneficial effects of soy protein have been attributed to its active component -the phytoestrogens or the isoflavones INTRODUCTIONMenopause is a normal life transition in a woman's life when reproductive capacity ceases due to loss of ovarian function resulting in a decrease in circulating estrogen levels (1). It is an objective hormonal event associated with subjectively perceived endocrine transition, resulting in various short-term vasomotor (hot flashes, mood swings, depression, nervousness, irritability) and urogenital symptoms (recurrent vaginitis, dysuria etc) and long-term sequelae-osteoporosis, Alzheimer's disease and Coronary Artery disease (CAD) (2).