Die Aminothiazole (I) kondensieren mit den α‐Bromketonen (II) zu den Derivaten (III), die zu den Imidazothiazolen (IV) cyclisiert werden (mittel bis gute Ausbeuten an (III) und (IV)).

Die Titelverbindungen (II), (III) und (IV) bzw. (VI) werden ausgehend von den entsprechenden Triazolen (I) bzw. dem Triazin (V) dargestellt.

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Heterocyclic system containing bridgehead nitrogen atom. Bart W. Received December 17, 1968The syntheses of 3-substituted-, 2,3-disubstituted-5,6-dihydro-4H-imidazo[2,1-b]thiazoles and 3-substituted-, 2,3-disubstituted-4,5,6,7-tetrahydrothiazolo[3,2-a]pyrimidines have been achieved by reacting ketones with 2-mercaptoimidazoline and 2-mercapto-3,4,5,6-tetrahydropyrimidine respectively in the presence of iodine. The condensation has also been affected by replacing iodine with bromine.Canadian Journal of Chemistry, 47,2843 (1969) In view of the broad spectrum anthelmintic interest to improve upon the methods of synactivity of dl-6-phenyl-2,3,5,6-tetrahydro-4H-thesizing condensed thiazoles. The present imidazo [2,1 -b]thiazole hydrochloride (tetra-communication reports the synthesis of two misole-HC1) (1-3), it was thought of considerable such systems.