Background: Acne vulgaris is a common chronic skin disease involving blockage and/or inflammation of pilosebaceous units (hair follicles and their accompanying sebaceous gland). Acne can present -non-inflammatory lesions (open and closed comedones), inflammatory lesions (papules, pustules, and nodules), and varying degrees of scarring or a mixture of both, affecting mostly the face but also the back and chest. Acne leads to significant morbidity that is associated with residual scarring and psychological disturbances such as poor self-image, depression, and anxiety, which leads to a negative impact on quality of life. Subjects and Methods: Total 200 patients divided into two groups of 100 each. One group was treated with dermaroller every four weeks for a period of 24 weeks and the other group was treated with fractional CO2 laser again every four weeks for a period of 24 weeks. Results: Six patients in dermaroller and nine patients in fractional CO2 laser group developed hyperpigmentation post procedure. Conclusion: Itching is not seen as a complication in the treatment with derma-roller, but in case of fractional CO2 laser group, a very small percentage of patients experienced itching a few days after the treatment due to peeling off of the scab that was formed after treatment.

BACKGROUND AND OBJECTIVES: Phrynoderma is a form of follicular hyperkeratosis that is associated with nutritional deficiencies. It is endemic to poor population and constitutes significant cases in dermatological clinics in India. The present study is undertaken to find out the therapeutic response in Phrynoderma cases. METHODS: A total of 100 patients with Phrynoderma after clinical diagnosis, who consented for study were included. Patients were divided into three groups of 34, 33 and 33 each. Following treatment regimens were given for each group. R1: Oral Vitamin A 50,000 IU daily for 8 weeks R2: Oral Vitamin E 100 IU daily for 8 weeks R3: Safflower Oil 1 tsp TD w/ meal for 1 month RESULTS: In a total of 100 patients of Phrynoderma studied; incidence was found to be 0.45% of which males were 63% and females were 37%. The male to female ratio was 1.70:1. Therapeutic response was better in R1 (Oral Vitamin A) group compared to R2 (Oral Vitamin E) group. Amongst R2 and R3 (safflower Oil), R2 showed better response compared to R3.