Background:The optimal development of toddlers requires both support and control from parents. Support refers to the emotional warmth that parents give to their children, as well as their supportive acts with respect to the individual needs and plans of their children. The aim of the study: The study aimed to assess the health problems of toddler after mother deprivation and evaluate the effect of mother deprivation on growth and development of toddler. Research design: Descriptive design utilized in carrying out of this study. Subject: A Convenient sample composed of 100 of toddlers at the outpatient clinics and emergency department of Pediatrics University Hospital. Tools: A structured Interviewing Sheet to assess health problems of toddler and toddler physical examination sheet and likert scale sheet. Results: 65.2% the studied toddlers with maternal deprivation had health problems, 43.5 % of the studied toddlers with maternal deprivation had moderate growth and development and 36.5% of them had slow growth and development. Conclusion:Based on the study finding it concluded that, there are statistical significant differences between child lives with, duration of deprivation from the mother, cause of deprivation of mother, availability of the father with the child and their growth & development. In addition, there is statistical significant difference between growth & development of the studied toddler with maternal deprivation and their health problems. Recommendation: Maternal deprivation children need better rearing care, with physical and psychological support, particularly those with fathers.