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. 1994. Counteraction of the follicular inhibitory effect of follicular fluid by administration of FSH in heifers. Can. J. Anim. . The hypothesis that a factor in follicular fluid suppresses fo[icular growth independently of reduced systematic FSH concentrations in cattle was tested in a 2 x 2 factorial designed experiment 1n : 5 hJifers group r;. Treatment, at lz-h intervals, began on day O (ovulation) and ended on day l. Mean (f SEM) diameter of the largest fotUcG, averaged over all days, and maximum diameter attained on days 0-9 was smaller (P < 0.05) in heifers given follicular fluid (8.4 t 0.+ ana D.4 t l.O mm, respectively) than in heifers given either saline (10'3 t 0'6 and t+.4 t 0.6 mm) or follicular fluid plus FSH (10.7 t 0.6 and 16.8 t 0.4 mm). The day+o-day mean diameter prohles of !$ the largest and secondlargest follicles for days 0-9 were similar among heifers given saline, follicular fluid plus FSH, and^FSH alone, whereas the follicle profile was reduced in heifers given follicular fluid alone. Mean follicle diameters were smaller (P < 0.05) on days 4-9 and days 2 ind 5 in heifers given follicular fluid than in heifers given either saline or follicular fluid plus FSH. jouiainsi qu'aux 2" et 5"jours chez les g6nisses recevant le liquide folliculaire que chez celles recevant le solut6 ou le liquide folliculaire avec FSH. Les r6sultats ne confortent pas I'hypothdse de d6part, puisque I'effet de la FSH exogEne I'emportait sur I'action inhibitrice attribu6e au traitement au liquide folliculaire.

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