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Two-block wood joints were obtained by insertion and welding without adhesives of dowels by high-speed rotation. Their strengths were better than that obtained by poly(vinyl acetate) (PVAc) gluing. X-ray-microdensitometry analysis showed that a complete welding of the dowel to the substrate occurred and that a perfectly tight joint was formed. Isolation of the flow material allowed CP-MAS 13 C-NMR analysis of its composition with possibly low interference from the constituents from the substrate. The flow material appeared to be composed of hemicelluloses, apparently xylans, and lignin. Scanning electron microscopy coupled with the NMR analysis results showed that microfibrils of cellulose, in both amorphous and crystalline states, torn from the wood surface during welding, as well as very small proportions possibly of recrystallized xylans and furanic compounds formed by heat transformation of the carbohydrates, were present. The geometry of the dowel joint allowed the joint to maintain up to 88% of its initial tensile strength after 24-h immersion in cold water.

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In the present study, paclitaxel was archaeosomed to reduce side effects and improve its therapeutic index. Carriers have made a big evolution in treatment of many diseases in recent years. Lipid carriers are of special importance among carriers. Archaeosome is one of the lipid carriers. Paclitaxel is one of the drugs used to treat breast cancer which has some unwanted side effects despite its therapeutic effects. Archaeosomes were extracted from methanogenic archi bacteria and synthesized with a certain ratio of paclitaxel in PBS. The mean diameter of archaeosomal paclitaxel was measured by Zeta sizer instrument, Drug releasing of archaeosomal paclitaxel was examined within 26 h which results showed that the most drug releasing occurs during first 3 h. The cytotoxicity effect of archaeosomal paclitaxel on breast cancer's cell line was evaluated by MTT assay which results showed that the cytotoxicity effect of archaeosomal paclitaxel on breast cancer's cell line is more than that of the standard paclitaxel formulation. The results indicated that new drug delivery of paclitaxel using archaeosome, increases the therapeutic index of the drug.