(Folia Morphol 2015; 74, 3: 346-351)

Conclusions:If the image of fetal endocardium could be showed clearly by real-time three-dimensional echocardiography, we will easily obtain fetal heart ventricle volume data to study fetal heart growth and function. Objectives: To evaluate the fetal right ventricular function by using full volume real-time three-dimensional echocardiography (RT-3DE). Methods: One hundred and fifteen normal fetuses with a gestational age ranging from 20 to 40 weeks were studied. By using full volume RT-3DE, fetal right ventricular volumes were outlined and calculated by QLab analysis software. In 2DE the volumes were measured by Shimanaki rule and Simpson's method. The right ventricular enddiastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF) and cardiac output (CO) measured by three different calculations were compared. Results: There were 109 fetuses were recruited into study, 6 fetuses with poor echocardiographic images were excluded. The result showed that there were significant difference between Shimanaki rule and Simpson's method (P < 0.05). There were significant difference between Shimanaki rule and RT-3D (P < 0.05), too. There was no difference between Simpson's and RT-3DE (P > 0.05). Conclusions: RT-3DE provides an accurate volume measuring method for irregular shaped RV for its independent of geometric assumption in calculating volumes. It may offer a useful approach for better understanding the characteristic of fetal myocardial properties during fetal heart development. Then they are useful to evaluate the changing of the fetal heart function along with the advancing gestational ages. RT-3DE evaluation of the fetal heart right ventricular function is feasible and reproducible. OP12.05 OP12.06Full-volume three-dimensional echocardiographic assessment of left ventricular volume in healthy human fetuses Sir Run Run Shaw Hospital, Zhejiang University College of Medicine & Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou, ChinaObjectives: To evaluate the feasibility and accuracy of full volume three-dimensional echocardiography (FV3DE) for quantifying the left ventricular volume in healthy fetuses. Methods: Two hundred and twenty-two normal fetuses with gestational ages between 20 and 40 weeks were investigated. Full volume three-dimensional, two-dimensional (2D) and M-mode images were acquired by using a Philips iE33 system and data was processed offline using QLAB analysis software. Left ventricular end-systolic volume (ESV) and end-diastolic volume (EDV) were measured using semi automated border detection echocardiographic techniques, and compared with 2D biplane Simpson's method and M-mode Teichholz formula. Results: Thirty-six fetuses with poor three-dimensional images and 5 twin pregnancies were excluded, the study subjects consisted of 181 singleton fetuses. The highest concordance correlation (r = 0.987 for EDV, r = 0.988 for ESV; P < 0.001) was noted between 2D biplane Simpson's and FV3DE-derived values with a small bias (0.332 ml for EDV, ...