Intussusception is extremely rare in preterm neonates and is often confused with necrotizing enterocolitis leading to considerable delay in its diagnosis. We present a case report of a preterm with colo-colic intussusception, which was diagnosed preoperatively using ultrasound. We examine the pitfalls in diagnosing intussusception in preterm neonates. Intussusception, though rare, should be considered in the differential diagnosis while managing a preterm with abdominal symptomatology. Abdominal ultrasound is useful in diagnosing intussusception in neonates.