α-Aminophosphonates play an important role across several fields, including organic synthesis and various potential applications. This review paper surveys recent achievements in the synthesis of α-Aminophosphonates, it summarizes the main synthetic routes towards α-Aminophosphonates that are known and it describes their biological proprieties from January2010 till December 2020: Special attention is devoted to green chemical approaches including catalysts, ultrasonic and microwave irradiations. We hope this paper will be a useful resource for researchers and that it will help them to work in this emerging research area.
A new environmentally benign, simple, and efficient protocol for the sulfonylation of amines using microwave irradiation under solvent- & catalyst-free conditions is reported. The corresponding sulfonamides were obtained in excellent yields within short reaction times.
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