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<span lang="EN-US">Substitution boxes are essential nonlinear modules that are popular in block ‎cipher algorithms. They ‎also play a significant role in the security area because of ‎their robustness to different linear ‎cryptanalysis. Each element of the state in a S-‎box is nonlinearly replaced using a lookup table. This ‎research presents the S-‎box, one of the fundamental parts of the advanced encryption standard ‎‎(AES) ‎algorithm. The S-box represents the confusion part in the AES. However, when ‎information ‎is shared between different devices in an authorized manner, the ‎algorithm should be able to ‎combine a sufficient number of confusion layers to ‎guarantee the avalanche effect (AE). ‎Subsequently, this research selects the best ‎S-box by comparing different sizes (4×4, 8×8, and ‎‎16×16) and measuring them ‎on the basis of the million-bit encryption. The AE is the main criterion ‎used in ‎choosing the best S-box. A robust and strong cryptography algorithm should be ‎able to ‎confirm the AEs. Results indicate that the 16×16 S-box with a 52% AE ‎ratio is the superior S-box</span>

Bitcoin it is digital currency used for any Electronic Financial Transactions, created in 2008 by Satoshi Nakamoto as Peer-to-Peer Electronic System cash. The precise prediction of bitcoin exchange rate with respect to the US dollar is an essential matter because it effected on the world economic constancy. Meanwhile the technology that used in Bitcoin has flickered a revolution in world. This paper aim to a survy on the use artificial neural networks to predict the exchange rate of a Bitcoin(BTC) currency.