Objective: Breast cancer is the most widely cancer among women, involving 18% of all female cancers, and worldwide, breast cancer is the fifth most common cause of cancer mortality. The study was designed to determine and compare the levels of Serotonin (ST), Melatonin (MT), Estradiol (E2), and Adiponectin (ADP) Hormones in Breast cancer patients and apparently healthy individuals. Material and Methods: Blood Serotonin (ST), Melatonin (MT), Estradiol(E2), and Adiponectin (ADP) Hormones levels were determined in 85 Breast cancer patients and 55 apparently healthy subjects. Results: The levels of serum Serotonin (ST), Melatonin (MT), and Adiponectin (ADP) Hormones were showing significant decrease in Breast cancer patients as compared to control group. ( P ≤ 0.05 ).While the level of serum Estradiol (E2) was showing significant increase in Breast cancer patients as compared to control group.( P ≤ 0.05 ). Conclusion: In Breast cancer patients, we finding decrease in Serotonin (ST), Melatonin (MT), and Adiponectin (ADP) Hormones. While we finding increase in Estradiol (E2) in Breast cancer patients as compared to control group.

The Indian medical systems hold promise for the genus Alstonia. Different types of Alstonia, primarily Alstonia scholaris, have been used by the various ethnic communities in India to treat various human illnesses. A historically significant medicinal herb is Alstonia scholaris. The Indian subcontinent and Southeast Asian nations are the native habitats of this evergreen tree. The plant is used in conventional, Ayurveda, Unani, homoeopathic, Sidhha/Tamil, and other alternative medical systems to treat a variety of illnesses, including asthma, malaria, fever, dysentery, diarrhea, epilepsy, skin conditions, and snakebites, among others. Alkaloids make up the majority of reported phytochemicals. In this review, reports on pharmacological and phytochemical varieties of A. scholaris are compiled.

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The most malicious tumor in women is breast cancer. Its treatment at the early stage of its recognition in a woman provides her multiple options for diagnosis. Physical inspection and mammography are helpful screening processes for the primary recognition of breast cancer, they are also labor dependent and need health specialists who are exceptionally prepared and skilled. This experiment was designed to estimate and compare the CA15-3 level, hormone, and Lactate dehydrogenase enzyme in Breast Cancer patients and in apparently healthier individuals. Blood CA15-3, hormone, and Lactate dehydrogenase enzyme levels were determined in 65 Women with Breast Cancer and 55 apparently healthy subjects. The levels of serum CA15-3, hormone, and Lactate dehydrogenase enzyme were showing a significant increase in women with Breast Cancer in comparison to the control group (P ≤ 0.05). The study also investigates the correlation between the concentrations of the CA15-3 and each of hormone, and Lactate dehydrogenase enzyme, However, we compared all measurement parameters according to the type of disease. In Breast cancer patients, we increase CA15-3, hormone, and Lactate dehydrogenase enzyme can clearly occur, and we positive correlation relationship between CA15-3 and each of PRL and LDH through coefficient correlation (r).

Acute coronary syndrome (ACS) is a group of clinical syndromes characterized by rupture or invasion of coronary atherosclerotic plaque, resulting in complete or incomplete coronary occlusion. The present study was designed to determine and compare the levels of hsCRP ,myocardial enzymes (CPK,LDH) and Oxidative stress (MDA, Cp, Tf) among patients with (ACS)&healthy individuals &asses the titer of hsCRP among different types of ACS to predict its role in risk stratifications of Acute coronary syndrome and healthy individuals. Serum high sensitivity C reactive protein , creatine phospho kinase, lactate dehydrogenase malondialdehyde , ceruloplasmin , and transferrin levels were measured in 100 patients Acute coronary syndrome and 70 supposed healthy subjects. The levels of serum high sensitivity C reactive protein ,creatine phosphokinase, lactate dehydrogenase, malondialdehyde, and ceruloplasmin , were reveled significant increase among patients with coronary artery disease as compared to control group whereas the levels of transferrin(Tf) showed a significant decrease in coronary heart disease patients in comparison to control subjects( P ≤ 0.01 ). This study was also revealed the correlation between the concentrations of the measured parameters and hsCRP .This study revealed significant in hsCRP among patients with ACS. This study revealed significant in hsCRP among patients with ACS. Lipid peroxidation &oxidative stress is more prominent among patients with ACS comparison to healthy individuals , & this is mostly the leading cause of atherosclerotic processes & resultant complication of coronary occlusion .