This chapter describes a systematic investigation of blockchain technology and its applications across various domains with the main focus on libraries. The concept and working of blockchain technology are discussed with respect to multiple domains to emphasize how the peculiar attribute of this technology can revolutionize ‘library practices'. The chapter presents the opportunities available for library professionals and awareness of this emerging technology and assist them in taking some initiatives for its appropriate application in libraries. It therefore concludes by recommending that the Librarian Registration Council of Nigeria in collaboration with Nigerian library professionals set up a blockchain website, blogs, and webinars to engage researchers, students, and information professionals to harness their inputs towards developing a whitepaper (policy) and promotion of emerging technologies for better services delivery in the libraries, adding value to libraries and the communities they serve.