A new prosthetic group is reported for quantitative 18F-labelling of peptides and proteins based on the chemoselective ligation of potassium acyltrifluoroborates (KATs) and hydroxylamines without any detectable 18F/19F isotope exchange at the KAT moiety.

In memory of our colleague and friend Professor François Diederich Chemical ligation reactions of functional groups that can be masked with two-photon labile protecting groups provide a powerful technology for the three-dimensional patterning of molecules-including proteinsonto hydrogel scaffolds. In order to utilize readily prepared hydrogels constructed by the potassium acyltrifluoroborate (KAT)-hydroxylamine amide formation ligation for two-photon patterning, we have developed a unique post-polymerization protecting group strategy through the reaction of KATs and dithiols in water and deprotection by two-photon excitation. After precise 3D spatially confined light irradiation, the unprotected KATs undergo ligations with hydroxylamine-functionalized superfolder GFP and sulforhodamine B for the composition of three-dimensional patterns.

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To improve the water-resistance of the MgO-based metal-insulator-metal (MIM) capacitors, BeO/MgO/BeO/MgO/BeO (BMBMB) stacked layers with a total thickness of ~ 10 nm (2/2/2/2/2 nm) were deposited at 335°C by atomic...

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