A new cytotoxic roridin-type trichothecene macrolide named roritoxin E(1) was characterized from the solid culture of Myrothecium roridum IFB-E091 (residing originally inside Artemisia annua root), together with the known compounds lumichrome (2), (22 E,24 S)-cerevisterol (3), and (22 E,24 R)-6 beta-methoxy-ergosta-7,22-diene-3 beta,5 alpha-diol (4). The structure of the new macrolide (1) was elucidated by a combination of spectroscopic (UV, IR, MS, and 1D and 2D NMR) analyses. Compound 1 was demonstrated to be inhibitory in vitro against the gastric carcinoma SGC-7901 and hepatocarcinoma SMMC-7721 cell lines, with IC (50) values of 0.26 and 10.54 microg/mL, respectively. 5-Fluorouracil co-assayed as a positive control had an IC (50) value of 6.66 microg/mL against SGC-7901 cells, and it demonstrated only a 9.98 % growth inhibition against SMMC-7721 cells at 10 microg/mL.
The argon-hydrogen co-injection tests were carried out in a multifunction ladle furnace (LF) equipped with a hollow graphite electrode. About 80 kg low carbon steel were refined in LF, the argon-hydrogen gas mixtures were injected onto the melt through the hollow graphite electrode, the flow rates of the gas mixtures were 3 m3/h. Then, applying the plasma local equilibrium thermodynamics and metallurgical thermodynamics theories, a calculation model of argon-hydrogen plasma component concentration was established. Using this model, the particle densities of the argon-hydrogen system were calculated. The decarburization mechanisms during Ar-H2 injection in LF with hollow graphite electrode were studied. The results show that, in the process of traditional LF refining, the carburetion reaction occurs with using the graphite electrode. When the argon-hydrogen was injected into LF, there was a decarburization reaction on the interface of the melt. Compared with the traditional LF, the carburetion rate reduces 33.3% at least. The partial pressure of C2H2 produced by molecule hydrogen is far lower than that of CH4 reacted by monatomic hydrogen. The possible main reactant gas is monatomic hydrogen and the main product is CH4.
Combined scale of the phase characteristics, let the hang iron machine as an example, this paper introduces the type of steam and steam appliances unit, analyses the formation mechanism of scale in steam equipment from the perspective of the chemical and physical, and studies the influence between structure of steam plant and the formation of boiler scale, loss, and sewage. A reasonable design solution is proposed through the analysis of various factors.
At present, China is the country with the maximum quantity of annual new construction in the world, but the average life of the buildings is very short. Through the analysis of the urban per capita living space of macro data variations and individual environmental psychology, it is raised that design lacks of “redundancy" is one of the important reasons.”Redundancy" is to consider the future needs in design , "redundancy" concept is introduced in the field of architecture, for solving that our country’s building lives are generally in a short situation. It is also an important way to realize the sustainable development.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.