Esophageal cancer remains a significant cause of cancer‐related mortality among men and women in the United States. The utility of surgery, as either an immediate or delayed resection in the form of esophagectomy following neoadjuvant therapy in local‐regionally advanced esophageal cancer, remains controversial. While neoadjuvant therapy followed by immediate surgery is a guideline‐concordant treatment, emerging data suggests that active surveillance with delayed resection at the time of local‐regional recurrence may be considered.

No abstract