Our findings indicated that maternal mosaicism of sex chromosome could cause discordant sex chromosomal aneuploidies associated with NIPT. We highly recommended that maternal karyotype should be confirmed for the cases with abnormal results in NIPT.

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A cascade-arch-firing low-NO x and high-burnout configuration (CLHC) was proposed as a solution for the W-shaped flame furnace's incompatibility problem of strengthened low-NO x combustion and high burnout. Numerical simulations verified by industrial-size measurements of a 600 MW e W-shaped flame furnace were used to confirm the CLHC's low-NO x and high-burnout characteristics and evaluate its cascade-arch configuration effect on the gas/particle flow, coal combustion, and NO x formation. The furnace with the existing low-NO x combustion art showed NO x emissions of about 900 mg/m 3 at 6% O 2 and carbon in fly ash of about 5%. In applying CLHC as a replacement for the prior art, numerical simulations at typical cascade-arch configurations of C L = 1/5, 1/4, and 1/3 (C L signifying the ratio of the lower arch depth to the total arch depth) showed that as C L increased, both the flow field and combustion symmetry initially improved but then deteriorated. In conjunction with the improvement in both NO x emissions and burnout, the C L = 1/4 setting achieved the best furnace performance with NO x emissions 707 mg/m 3 at 6% O 2 and carbon in fly ash of 5.5%. In comparison with the prior low-NO x art, CLHC reduced further NO x emissions by 22% and almost maintains the burnout rate.

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