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Discovery of 7-Methoxy-6-[4-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-5-yl]--1,3-benzothiazole (TASP0382088): A Potent and Selective Transforming Growth Factor-β Type I Receptor Inhibitor as a TopicalDrug for Alopecia. -The title compound (I) is a selective and potent ALK5 inhibitor. It shows good enzyme inhibitory activity as well as inhibitory activity against TGF-β-induced Smad2/3phosphorylation at cellular level. -(AMADA*, H.; ASANUMA, H.; KOAMI, T.; OKADA, A.; ENDO, M.; UEDA, Y.; NARUSE, T.; IKEDA, A.; Chem. Pharm. Bull. 61 (2013) 3, 286-291, http://dx.