Multiple primary malignant tumors in the same individual occur more frequently than one would expect, yet metastasis of one cancer to another independent cancer is an uncommonly reported finding. The present report adds to the past literatures a case of metastasis of gastic cancer to hypernephroma and furthermore even to sites of metastasis of hypernephroma. An attempt to clarify the correlation of two tumors and tumor-host relationship was made in comparison with experimental results of transplantable induced double cancer (DAB hepatoma and MC sarcoma) of the rat in our laboratory, CASE REPORTA 65-year-old Japanese male was admitted to the Numata Kosei Hospital on December 30, 1962. Neuralgia of both legs had begun in June, 1962. On admission, he complained of Severe neuralgic pains in the abdominal wall and back, motor paralysis and complete loss of sensitibility of the lower extremities. Disturbances of the vesical and rectal sphincters and atrophy of both legs were noticed. Destruction of the dorsal column X, XI, & XI1 were confirmed by Roentgen examination. Several small subcutaneous nodules were noticed on the chest and abdominal walls. Biopsy of the nodule revealed a metastasis of undifferentiated carcinoma. Indistinct induration was palpable in the upper abdomen. Roentgen examination revealed rigidity of the lesser curvature of the stomach. Clinical diagnosis was then carcinoma of the stomach and its metastases in the skin and dorsal column, resulting in complete transverse interrupture of the spinal cord. Anticancerous agents were ineffective.The patient expired on Feb. 5, 1963, approximately 8months after onset of the symptoms.

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