Acquired maxillary defects are created by surgical removal of benign or malignant tumors, congenital malformation and by trauma. Surgery is the fi rst choice for some benign tumors, early cancers and for cancers that do not respond to radiation and chemotherapy. Surgery or trauma can result in cosmetic, functional and psychological impairment greatly aff ecting the patient's quality of life. Surgical reconstruction of the maxillary defects can be carried out either by using temporal fl ap or a wide range of microvascularized fl aps. Rehabilitation via palatal obturators to obturate a palatal defect in a dentulous or edentulous patient is one of the choices in restoring masticatory function and improving speech, deglutition and cosmetics. Rehabilitation of such patients is quiet challenging and requires a multidisciplinary team for comprehensive care and optimal post-treatment functional outcomes. Hence, it is crucial to work in close collaboration with the team members who makes the prosthesis and who evaluates the case for planning the surgical procedures and obtaining the necessary anatomical and functional information.