No abstract

PEG-INF α2b) were predictors of SVR. Conclusion: Overall SVR among Sharkian patients with CHC, treated with SOC therapy is 50.8%. EVR is the best independent predictor of SVR. The form of PEG-INF may also predict the treatment response. None of the initial pretreatment variables could predict the SVR to treatment with the current SOC for CHC.

Patients with CC genotype were associated with lower level of IP10, ALT, AST and also low viral load. Patients with low level of IP10 had lower levels of liver enzyme. Cut off level of IP 10 was<605 pico gram/ml; at this cut off value sensitivity was=100%, specificity was= 96.7% and area under the curve (AUC)= 0.99. Conclusion: IP10 level was lower among responder group. IL28 genotype CC was significantly higher in responders when compared with non responders. .Patients with CC genotype were associated with lower level of IP10 and liver enzymes. Patients with CC genotype were associated also with low viral load.