After lung cancer colorectal cancer (Cc) is ranked the second, as a cause of cancer-related death. Th e purpose of this study was to analyze the Cc cases in our material with respect to all prognostic values including histological type and grade, vascular invasion, perineural invasion, and tumor border features. Th ere were investigated  cases of resection specimen with colorectal cancer, which were fi xed in buff ered neutral formalin and embedded in paraffi n. Tissue sections ((μm thick) were cut and stained with H&E. Adenocarcinoma was the most frequent histological type found in , of cases, in , of males and , of females; squamous cell carcinoma in ,, in , of males and , of females; mucinous carcinoma in ,, in , of males and , of females; while adenosquamous carcinoma, undiff erentiated carcinoma and carcinoma in situ in , of cases each. Dukes' classifi cation was used in order to defi ne the depth of invasion. Dukes B was found in , of cases, whereas in , of cases Dukes C was found. As far as histological grading is concerned, Cc was mostly with moderate diff erentiation (,) with neither vascular nor perineural invasion. Resection margins were in all cases free of tumor. Our data indicate that the pathologic features of the resection specimen constitute the most powerful predictors of postoperative outcome in Cc. Dukes' stage and degree of diff erentiation provide independent prognostic information in Cc. However, diff erentiation should be assessed by the worst pattern.

ObjectiveThe objective of this study is to explore the feasibility and efficacy of a new technique for sutureless vascular anastomosis, using glued prosthesis, as a sole anastomosis fixation method in rabbits.MethodsTen rabbits were randomly selected to conduct the experiment. Five rabbits underwent direct anastomosis of infrarenal abdominal aorta, with glued prosthesis. In five other rabbits, reconstruction was done by sutured anastomosis. All animals were immediately examined by echo-Doppler for patency of anastomosis. The burst pressure of the glued anastomosis was measured and compared with that of a sutured artery. The animals were euthanized, and tissue samples were taken for histological examination immediately after the experiment.ResultsCompared to conventional anastomoses, sutureless vascular anastomoses required shorter time of creation and significantly reduced blood loss (P<5%). There was no significant difference on the average blood flow through the anastomosis between two groups at the end of surgery. All anastomoses with glued prosthesis, examined by echo-Doppler, were patent at the anastomotic site, except one, which was stenosed immediately after surgery. In the control group, except one with stenosis, all conventional anastomoses were patent. Mean burst pressure at the anastomotic site for sutureless anastomoses was lower than in control group. Macroscopically, the BioGlue did not demonstrate any adhesion to the surrounding tissue as it was covered by the vascular prosthesis. Histological examination showed low-grade inflammatory reaction in glued anastomoses versus no inflammatory reaction at the sutured anastomoses.ConclusionThis technique may provide a feasible and successful alternative in vascular surgery. However, further long-term studies are necessary to elucidate the break pressure and degree of inflammation at the anastomotic site.

Th yroid cancer accounts for approximately  of total cancer cases in developed countries. Th e aim of this study has been to analyze the histopathological variants of thyroid tumours with regard to gender and age. Despite their relative rarity in our material, they exhibit a wide range of morphological patterns and biological behaviour. During the period from -,  biopsy cases of thyroid tumours, which were fi xed in buffered neutral formalin and embedded in paraffi n, have been reviewed. Tissue sections (μm thick) were cut and stained with hematoxylin and eosin (H&E). Follicular adenomas have been found in ,  of cases, thyroid carcinomas in , , whereas thyroid secondary carcinomas have been found in ,  of cases. As far as histological variants of thyroid carcinomas are concerned, most frequently found were papillary carcinomas in , of cases; followed by follicular carcinomas in , of cases; follicular variants of papillary carcinomas in , of cases; medullary carcinomas in , of cases, while anaplastic and Hurthle cell carcinomas have been found in , of cases each. All histological variants of thyroid tumours occurred more frequently in women than in men. Papillary carcinoma has been found in  of female cases. Th yroid tumours in our material mainly occurred in the third, the fourth and the fi fth decade of life. Our data indicate that apart from the fact that papillary carcinomas, well diff erentiated, and characterised by relatively good prognosis, were most frequent variants, certain morphological variants of it were associated with poor prognosis.

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The aim of this study was to investigate the relationship between mental well-being – as assessed by the SDQ among children with asthma in Kosovo and SES. Methods and Results: For this cross-sectional observational study, data were collected from five regions of Kosovo, public and private institutions, public hospitals and primary healthcare facilities in each area, a tertiary level hospital, and two private immunology clinics in the capital city. The survey included 161 Kosovar children (mean age of 11.1±2.7 years) with asthma, aged 7-16 years, and their caregivers. The survey questionnaires used were those of the American Academy of Pediatrics: The Children's Health Survey for Asthma (CHSA), the parent and child version (CHSA-C), and the Strengths and Difficulties Questionnaire (SDQ). SDQ showed conspicuous (borderline or abnormal) results in 25.1% of children. None of the scales of the SDQ, except prosocial behavior, showed statistically significant differences across SES categories. Prosocial behavior scores increased significantly with increasing SES. Conclusion: Children with asthma from lower SES families in Kosovo have more social contact problems but do not show reduced mental well-being nor more conduct problems.